What is sildenafil, and how does it work mechanism of action? Viagra sildenafil is an oral drug that is used for treating impotence or erectile disfunction, ED, the inability to attain or maintain a penile erection. It has been estimated that impotence affects million men worldwide. Over half of all men with impotence are thought to have some physical medical cause. The remainder are believed to have psychogenic causes of impotence. Medical causes of impotence include diabetes and circulatory, neurological, or urological conditions.
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The objectives of this study were to evaluate the efficacy and tolerability of high dose sildenafil as a salvage therapy for patients refractory to the maximum recommended dose of sildenafil. The mean age of the study group was Mean IIEF question 3 and 4 scores were 1. Erectile dysfunction ED is the inability to achieve and maintain an erection of sufficient rigidity for satisfactory sexual intercourse. Sildenafil citrate Viagra TM, Pfizer, UK, a potent, competitive phosphodiesterase type 5 iso-enzyme PDE-5 inhibitor, is the first oral medication to demonstrate significant and reliable efficacy in most patients with ED.
Sildenafil is used to treat male sexual function problems impotence or erectile dysfunction -ED. In combination with sexual stimulation, sildenafil works by increasing blood flow to the penis to help a man get and keep an erection. This drug does not protect against sexually transmitted diseases such as HIV, hepatitis B, gonorrhea, syphilis. Practice safe sex such as using latex condoms. Consult your doctor or pharmacist for more details. If you have any questions, ask your doctor or pharmacist.
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Try out PMC Labs and tell us what you think. Within 6 months of approval by the U. The chemical structure of sildenafil is very similar to the viagra 200mg blue guanosine monophosphate molecule with which it competes, in the enzyme phosphodiesterase type Sildenafil binds to the phosphodiesterase-5 enzyme, preventing the breakdown of cyclic guanosine monophosphate through competitive inhibition. The onset of action for sildenafil can be as short as 20 minutes and the duration of action may be as long as three half-lives 18 hours.
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One questions many people have is around how long it will be active for in their system. So, viagra 200mg blue is Viagra, how long does Viagra last, and what might affect this? This is when a man cannot get or keep a hard, erect penis suitable for penetrative sex. Viagra is one of a class of drugs known as PDE-5 Phosphodiesterase type 5 inhibitors. Viagra and the other PDE-5 inhibitors can help men with erectile dysfunction male impotence by enhancing the erectile response when a man is sexually stimulated.
Your doctor decides what treatment is best for you. Different dosages all work the same way and last about hours, with mg being an effective dosage for men who don't respond to lower doses. The dosage prescribed for you is based on your personal medical history and needs. The amount of a dosage varies based on the strength of your dose, how much you may take in a day, and how often you may take it. The most commonly prescribed Sildenafil Viagra dosage is 50mg.
Is Sildenafil the same as Viagra? Well, Sildenafil is the active ingredient in both branded Viagra and viagra 200mg blue unbranded Sildenafil tablets. Sildenafil and Viagra are PDE5 inhibitors, meaning they work by allowing blood vessels to expand and relax. The main difference between Sildenafil and Viagra is the branding and the price. Viagra tablets inevitably cost more than the generic Sildenafil medication. When researching your options for erectile dysfunction medications, the huge variety of brands on the market can be a pain to navigate.