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There are many disorders of the endocrine glands.
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In practice, Clinical Governance Leads are likely to be appropriate, but they can only do so as named individuals.
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Severe acute asthma is treated as an emergency with oxygen, inhalation of salbutamol and possibly inhaled antimuscarinics and intravenous and oral corticosteroids, intravenous salbutamol, aminophylline and antibiotics if necessary.
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Pathological features of Alzheimers disease are extracellular plaques of β-amyloid protein and neurofibrillary tangles. β-amyloid plaques are found particularly in the hippocampus and association areas of the cerebral cortex. Similar plaques are seen in unaffected individuals, but there are many more in patients with Alzheimers disease. Their formation may be due to abnormal metabolism of a precursor protein.
Neurofibrillary tangles are found in neurons and may be collections of abnormal microtubule proteins, which form as a result of cell destruction.