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Schon seit ist er nun in Deutschland, im Kreis Paderborn.
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That is, they preferentially block neurons that are transmitting action potentials at a high frequency (as occurs during an epileptic seizure) because more channels will be in the inactive state under such circumstances.
Rigidity, hypokinesia and tremor are all improved. Amantadine has few side effects, mainly gastrointestinal disturbances and ankle oedema, but becomes less effective over time as the dopaminergic neurones are progressively lost.
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