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The aim of drug therapy is to slow progression of the disease, but there is no cure. There are four groups of drugs, which augment the action of the dopaminergic system, plus anti-cholinergic drugs.
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If bone pain is severe or if the patient has neurological symptoms, or fractures that will not heal, calcitonin or bisphosphonates may be indicated. Calcitonin is the natural hormone that inhibits the activity of osteoclasts. Produced either from pigs or salmon or more recently from human sources by recombinant DNA technology, it is given daily by sub-cutaneous injections.
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