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Generic medicines contain the same active ingredient and are equally effective and equivalent as the branded products but are available at a lower price.
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Anaesthetic gases are the only group of drugs that are significantly excreted in expired air.
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Since the are non-ionic contrast agents and therefore do not dissociate in solution.
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Use is made of this in the treatment of thromboembolic disease.
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Both these actions result in raised levels of monoamines at the synapse.
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The mode of action of imidazoles is to make fungal cells leaky by inhibiting an enzyme necessary for ergosterol synthesis.
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With very severe resistant eczema, immunosuppressant drugs may be needed. Psoriasis is a chronic inflammatory skin disease with hyperproliferation of keratinocytes, which leads to thickening of the epidermis and typical silvery scales on the surface.
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Adverse effects include drowsiness, depression and postural hypotension especially in the elderly, which restricts their use to resistant hypertension. α be used in patients with an enlarged prostate or urinary incontinence. These drugs are used together with β-blockers and diuretics if necessary in resistant hypertension. The site of action is in the brain, probably the medulla, and the effect is to reduce sympathetic output.
Examples of centrally acting antihypertensives are methyldopa and clonidine.