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Adverse effects of neuraminidase inhibitors are bronchospasm with zanamivir, which is inhaled, and gastrointestinal disturbances with oseltamivir.
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Oral replacement of vitamin B by intramuscular injection of hydroxycobolamin, a form of vitamin B Folic acid deficiency can occur due to pregnancy, malabsorption syndromes or inadequate diet.
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They appear darker on X-ray film and are used to show the outline of surrounding soft tissue.
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Other techniques for local anaesthetic administration are given for the sake of completeness. EMLA (eutectic mixture of local anaesthetics; a combination of two local anaesthetics, lidocaine and prilocaine in a cream) is capable of producing skin thickness analgesia from topical administration.
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These drugs also show use-dependence. That is, they preferentially block neurons that are transmitting action potentials at a high frequency (as occurs during an epileptic seizure) because more channels will be in the inactive state under such circumstances.