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Eventually, whether metabolized or not, a drug is eliminated from the body. The usual route of excretion is via the kidneys and rate of elimination depends on rate of urine production, pH of urine and transport mechanisms. Although drugs do appear in faeces, expired air, sweat and breast milk, these are normally minor routes of excretion. The following two case studies could be of relevance to any health care professional.
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She wonders whether it could be due to the complex mixture of drugs she is taking and asks you what she should do about it. What should you tell her. You should be able to answer the following review questions from the topics covered in the preceding chapter. and how might you predict if a patient is likely to have an allergic reaction to a particular drug.