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Technicians are not legally permitted to use PGDs and as such cannot work within them. Neither can the use of a PGD be delegated by a radiographer. As a consequence of this, until recently, each adjunct medicine would have been approved by an independent prescriber on a patient-specific basis or the doctor themselves would have administered it.
Not surprisingly, this was a time-consuming process and as a result, on the advice of Administration of Radioactive Substances Advisory Committee, new legislation has been passed.
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Normally when impulses travel down a neuron to skeletal muscle the nerve endings release acetylcholine, which crosses the neuromuscular junction and brings about the activation of muscle contraction. In myasthenia gravis the receptors for acetylcholine on the muscle cell membrane are progressively destroyed by antibodies.