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Wherever possible, drugs should be prescribed by their generic name; this allows any suitable product to be dispensed and in many cases, it saves the health service money. The only exception to this rule is when a patient must always receive the same brand of a drug because different preparations can result in different blood levels of the drug. No details of dosages are given in this book, because these are subject to change and often have to be varied to suit individual patients.
In practice, the BNF or MIMS should be used as a guide to dosages. Examples of individual drugs have been kept to a minimum in the text, with usually just one or two examples given in each section.
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From such observations the monoamine theory of depression and mania was formed: Depression is due to an absolute or relative decrease in monoamines, or a decrease in receptor sensitivity, at certain receptor sites in the brain. Mania is due to an absolute or relative excess of monoamines or an increase in receptor sensitivity at these sites. Even after years of research, it is still not clear generic proscar prescription receptor sites or which monoamines are involved, although noradrenaline, serotonin and dopamine are all implicated.
Neither does the theory explain how mania and depression can exist in the same patient. Much research has involved investigation of cerebrospinal fluid, blood and urine of patients to see if there are any abnormalities of monoamine metabolites.
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