The efficacy and tolerability of Prinivil and Procardia XL were compared in 67 black, 68 white patients with mild to moderate uncomplicated essential hypertension. Patients received Prinivil 10 to 40 mg once daily or Procardia XL 30 to mg once daily during a titration period of 2 to 8 weeks to achieve the goal blood pressure before a 4-week maintenance period. Mean decreases in SDBP from baseline were comparable for both treatment groups. At the end of the titration period, mean decreases were 9. There were no differences in treatment responses in either the black or white hypertensive subgroups. Thus both drugs were equally effective in black and white patients with mild to moderate essential hypertension.
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Lisinopril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Lisinopril is used to treat high blood pressure hypertension in adults and children who are at least 6 years old. Lisinopril is also used to treat congestive heart failure in adults, or to improve survival after a heart attack. Do not use lisinopril if you are pregnant.

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When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus. When pregnancy is detected, lisinopril should be discontinued as soon as possible.
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It is used to treat high blood pressure and congestive heart failure. It works by relaxing blood vessels and helping the heart to pump blood that carries oxygen to the different parts of the body more efficiently.
Lisinopril is used alone or in combination with other classes of antihypertensive agents e. Because captopril, another angiotensin-converting enzyme ACE inhibitor, may cause serious adverse effects, e. Lisinopril is used alone or in combination with other classes of antihypertensive agents in the management of hypertension. ACE inhibitors are considered one of several preferred antihypertensive drugs for the initial management of hypertension; other options include angiotensin II receptor antagonists, calcium-channel blockers, and thiazide diuretics. While there may be individual differences with respect to specific outcomes, these antihypertensive drug classes all produce comparable effects on overall mortality and cardiovascular, cerebrovascular, and renal outcomes.

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