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It's thought to work by increasing the amount or mimicking the action of a neurotransmitter, GABA, in the brain, but the exact mechanism is unknown. Increasing levels of GABA may help prevent brain signals that lead to seizures. It was approved to treat bipolar disorder in, and in it was approved for use as a migraine prevention medication. Abbot Laboratories manufactures Depakote. In, Abbot Laboratories pleaded guilty to federal charges for marketing Depakote as a drug to control agitation and aggression in elderly nursing home patients. The FDA requires Depakote to carry a black-box warning because it can cause serious liver damage that could be fatal, especially in children younger than 2.
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Depakote is a medication known as an anticonvulsant that is used to treat the manic symptoms of bipolar disorder. It is also used to treat seizures and prevent migraine headaches.
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It's considering used to prevent migraine headaches and can also be used to treat epilepsy.
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Common side effects include nausea, vomiting, sleepiness, and dry mouth.
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It is also known to treat bipolar mania and to manage migraine headaches.
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It also is recommended that you wait to drive or operate machinery until you know how the medication affects you. Archived from the original on 6 June This condition resolved after discontinuing valproate therapy.
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