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NSAIDs are used in the treatment of chronic inflammation because they have a lasting analgesic action and an anti-inflammatory effect.
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NSAIDs are often needed for pain control and corticosteroids can be useful for reducing exacerbations of inflammation.
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Most antidepressants lead to the production of brain-derived neurotrophic factors that bring about neurogenesis and this could contribute to their effectiveness in depressed patients.
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Drugs can compete for the same protein binding sites and this is a form of drug interaction.
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