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Wanneer mannen seksueel opgewonden raken dan gaan hormonen, spieren, zenuwen en bloedvaten allemaal samenwerken om een erectie tot stand te brengen. Zenuwsignalen, verzonden van de hersenen naar de penis, stimuleren de spieren om te ontspannen. Hierdoor kan het bloed naar de penis stromen. Als het bloed de penis vult en de erectie is een feit dan worden de bloedvaten naar de penis afgesloten zodat de erectie kan worden aangehouden. Na de seksuele opwinding gaan de bloedvaten en aders van de penis weer open zodat het bloed weer uit de penis kan. Op een bepaald moment in het leven van een man is er een grote kans dat hij problemen zal krijgen met het krijgen of behouden van een erectie.
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Phenothiazines have pronounced sedative effects. They are also antiemetic (due to the blocking of dopamine receptors in the chemotrigger zone) and cause increased levels of prolactin (by inhibition of the effects of dopamine in the hypothalamic-pituitary pathway, and women. This group of drugs is similar to phenothiazines with mode of action by block of dopamine D are very similar. An example from this group is flupenthixol.
Side effects of thioxanthines are as expected, being antiemetic, Parkinsonism, tardive dyskinesia and raised prolactin levels. This group of anti-psychotic drugs has a similar mode of action and side effects to the phenothiazines.