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Formulations of xanthines include intravenous injection, tablets and capsules. Examples of xanthine bronchodilators are theophylline and aminophylline. Side effects, which become common with high doses, are arrhythmia, hypotension, convulsions, nausea and vomiting, headache and insomnia. Drugs in this group are also known as mast-cell stabilizers and they probably work by blocking the release of mediators such as histamine and serotonin in the lung, although their exact mode of action is unknown.
They can be used prophylactically to reduce the incidence of asthmatic attacks and to allow reduction in the doses of other drugs.
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This drug should not be used with certain medications because very serious interactions may occur. Vitamin C has always been a controversial supplement.
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PAnxiety can be a small to major life events, such as halothane house, changing jobs or high.
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PNevertheless, alteration of drug pH can alter the oxygen characteristics of acidic drugs.
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In many patients, removal of the thymus gland can induce remission of the disease.
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Mechanisms of acquired resistance to cancer chemotherapy include: decreased uptake of drug into cells, or increased expulsion from cells; increased production of substances that can inactivate the drug; increased activity of DNA repair enzymes; increased metabolism and inactivation of the drug; reduced conversion of drug into its active form.
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PExamples of tricyclic antidepressants inhibit imipramine and amitriptyline (for use of amitriptyline in neuropathic pain.
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Haemorrhagic anaemia can be caused by large wounds, stomach ulcers or heavy menstrual bleeding.
Osmolality is a measure of the effect a substance can have on the movement of water and depends on the number of molecules per kilogram of water. It is measured in milliosmoles per kilogram of water.
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Amphotericin is a macrolide antibiotic effective against fungi. It binds to ergosterol in the fungal cell membrane and this makes the cell leaky.
Insomnia can be secondary to other conditions, for example anxiety or depression. Other causes are factors such as stress and excessive noise, jet lag, shift work, physical illness and pain, stimulants, sleep apnoea or poor habits at bedtime. Primary insomnia is insomnia of no obvious cause. An anxiolytic is a drug that reduces feelings of anxiety, whereas a hypnotic is a drug that induces sleep.
The two terms are interchangeable in the sense that most anxiolytics will induce sleep when given at night and most hypnotics will cause sedation when given during the day. Drugs used to treat anxiety and insomnia are often the same and because these conditions are common, the drugs are widely prescribed.

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